Compound | HM-71224 | ||||
---|---|---|---|---|---|
CAS No. | 1353550-13-6 | Catalog No. | T0032 | Brand | |
Purity | 99% | Packing | 1kg | Grade | |
Lead Time | 14Day (s) | Origin | Loading Port |
Olmutinib is a novel third-generation epidermal growth factor receptor (EGFR) mutation-specific tyrosine kinase inhibitor (TKI). Also a potent inhibitor of Bruton's tyrosine kinase.
HM61713 causes potent inhibition in cell lines H1975 (L858R and T790M) and HCC827 (exon 19 deletion). It has a low potency for NSCLC cell line H358 harboring wild-type EGFR (GI50 of 2225 nM)
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N-(3-{2-[4-(4-methylpiperazin-1-yl)phenylamino]furo[3,2-d]pyrimidin-4-yloxy}phenyl)acrylamide
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