N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]propanamide1214265-58-3,Purity99%

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Catalog No. : T0029

N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]propanamide

CAS No : 1214265-58-3
Packing : 1kg
Brand :
Purity : 99%
Loading Port :
Lead Time : 14Day (s)

Packing :

1kg

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Compound	N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]propanamide
CAS No.	1214265-58-3	Catalog No.	T0029	Brand
Purity	99%	Packing	1kg	Grade
Lead Time	14Day (s)	Origin		Loading Port

Description

WZ4003 is a highly specific NUAK kinase inhibitor with IC50 of 20 nM and 100 nM for NUAK1 and NUAK2 in cell-base assays, respectively, without significant inhibition on 139 other kinases.

In HEK-293 cells expressing wild-type NUAK1, WZ4003 (310 M) markedly suppresses NUAK1-mediated MYPT1 phosphorylation. Moreover, WZ4003 (10 M) inhibits MYPT1 Ser445 phosphorylation as well as cell migration, invasion and proliferation to a similar extent as knock out in MEFs or knock down in U2OS cells of NUAK1. WZ4003 also exhibits a high, specific affinity to the L858R/T790M mutant EGFR, while a significantly reduced cellular IC50 against T790M containing Ba/F3 cells.

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Product: N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]propanamide

Cas No: 1214265-58-3

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Product Name	Purity	Packing	Lead Time	Country	Store Name	Details
WZ4003	98%	1kg	IN STOCK	China,Zhejiang	Hangzhou J&H Chemical Co., Ltd.	Request For Quotation
WZ4003	0.98	2g	3Day (s)	China,Henan	Henan Coreychem Co.,Ltd	Request For Quotation
N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]propanamide	98%	1kg,1吨	7Day (s)	China,Zhejiang	Hangzhou DayangChem Co., Ltd	Request For Quotation
N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]propanamide	98%	5mg	7Day (s)	United States,New Jersey	MedChemexpress LLC	Request For Quotation
N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]propanamide	98%	5mg	7Day (s)	China,Zhejiang	Hangzhou Guangyuan Biotechnology Co., Ltd.	Request For Quotation
N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]propanamide	98%	5mg,50mg	3Day (s)	China,Shanghai	ShangHai WeiHuan Biotech CO.,Ltd	Request For Quotation
N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]propanamide	99%	5mg,25mg	1Day (s)	Netherlands,	Axon MedChem BV	Request For Quotation
N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]propanamide	98%	10mg,50mg	7Day (s)	China,Sichuan	Chengdu SinoStandards Bio-Tech Co.,Ltd.	Request For Quotation
N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]propanamide	98%	100mg	15Day (s)	China,Shanghai	Shanghai Anfen chemical Co.,Limited	Request For Quotation
N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]propanamide	99%	10g,1g	3Day (s)	China,Shanghai	Shanghai Beihao Er Biological Technology Co., Ltd.	Request For Quotation

Product Name

Purity

Packing

Lead Time

Country

Store Name

Details

WZ4003

98%

1kg

IN STOCK

China,Zhejiang