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Compound | fingolimod hydrochloride | ||||
---|---|---|---|---|---|
CAS No. | 162359-56-0 | Catalog No. | XMZX-W5645 | Brand | |
Purity | 99% | Packing | 25kg/DRUMS | Grade | |
Lead Time | 3Day (s) | Origin | Loading Port | China,Xiamen,Siming District |
Boiling Point | 479.5ºC at 760 mmHg |
---|---|
Appearance & Physical State | white solid |
Flash Point | 243.8ºC |
Refractive Index | 1.531 |
Density | 1.016g/cm3 |
Melting Point | 102-107ºC |
Vapor Pressure | 5.28E-10mmHg at 25°C |
Chemical Properties White Solid
Originator Yoshitomi Pharmaceutical Industries (now Mitsubishi Tanabe Pharma) (United States)
Uses A derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analogue of Sphingosine. It is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibitin
Uses Oral medicine for the treatment of multiple sclerosis
Uses FTY720 is a derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analogue of Sphingosine. FTY720 is a novel immune modulator that prolong s allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs. FTY720 us reported to be phosphorylated by sphingosine kinase to FTY720-P, which has been shown to potently stimulate GTPgS binding activity in S1P-transfected CHO cells (EC50 = 210 pM, 4.9 nM, 4.3 nM, and 1 nM for S1P1, S1P3, S1P4 and S1P5, respectively).
Uses A cell-permeable aminopropanediol immunosuppressive agent that displays lymphocyte sequestration properties.
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