1.Identification

1.1 GHS Product identifier

1.2 Other means of identification

1.3 Recommended use of the chemical and restrictions on use

1.4 Supplier's details

1.5 Emergency phone number

2.Hazard identification

2.1 Classification of the substance or mixture

Acute toxicity - Dermal, Category 4

Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

2.2 GHS label elements, including precautionary statements

Pictogram(s)
Signal word	Warning
Hazard statement(s)	H312 Harmful in contact with skin H400 Very toxic to aquatic life
Precautionary statement(s)
Prevention	P280 Wear protective gloves/protective clothing/eye protection/face protection. P273 Avoid release to the environment.
Response	P302+P352 IF ON SKIN: Wash with plenty of water/... P312 Call a POISON CENTER/doctor/…if you feel unwell. P321 Specific treatment (see ... on this label). P362+P364 Take off contaminated clothing and wash it before reuse. P391 Collect spillage.
Storage	none
Disposal	P501 Dispose of contents/container to ...

2.3 Other hazards which do not result in classification

none

3.Composition/information on ingredients

3.1 Substances

4.First-aid measures

4.1 Description of necessary first-aid measures

General advice

Consult a physician. Show this safety data sheet to the doctor in attendance.

If inhaled

If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.

In case of skin contact

Wash off with soap and plenty of water. Consult a physician.

In case of eye contact

Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.

If swallowed

Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

4.2 Most important symptoms/effects, acute and delayed

Excerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]: Inhalation of material may be harmful. Contact may cause burns to skin and eyes. Inhalation of Asbestos dust may have a damaging effect on the lungs. Fire may produce irritating, corrosive and/or toxic gases. Some liquids produce vapors that may cause dizziness or suffocation. Runoff from fire control may cause pollution. (ERG, 2016)

4.3 Indication of immediate medical attention and special treatment needed, if necessary

Skin decontamination. Wash skin with soap and water ... . Eye contamination should be removed by prolonged flushing of the eye with copious amounts of clean water or saline. If irritation persists, obtain specialized medical treatment. Sensitization reactions may require steroid therapy. /Haloaromatic substituted ureas/

5.Fire-fighting measures

5.1 Extinguishing media

Suitable extinguishing media

Wear self contained breathing apparatus for fire fighting if necessary.

5.2 Specific hazards arising from the chemical

Excerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]: Some may burn but none ignite readily. Containers may explode when heated. Some may be transported hot. For UN3508, be aware of possible short circuiting as this product is transported in a charged state. (ERG, 2016)

5.3 Special protective actions for fire-fighters

Wear self-contained breathing apparatus for firefighting if necessary.

6.Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.

6.2 Environmental precautions

Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.

6.3 Methods and materials for containment and cleaning up

Use personal protective equipment. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust.

7.Handling and storage

7.1 Precautions for safe handling

Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Store in a dry location.

8.Exposure controls/personal protection

8.1 Control parameters

Occupational Exposure limit values

no data available

Biological limit values

no data available

8.2 Appropriate engineering controls

Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

8.3 Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

Respiratory protection

Wear dust mask when handling large quantities.

Thermal hazards

no data available

9.Physical and chemical properties

10.Stability and reactivity

10.1 Reactivity

no data available

10.2 Chemical stability

Decomposition: < 0.5% after 1 day storage at 100°C; < 0.5% after 7 days at 50°C. The solid is stable to sunlight. Decomposition at 20°C in aqueous solution after 21 days in the dark is: 4% at pH 5.8, 8% at pH 7, 26% at pH 9.

10.3 Possibility of hazardous reactions

A urea derivative.

10.4 Conditions to avoid

no data available

10.5 Incompatible materials

Diflubenzuron hydrolyzes in water to p-chlorophenylurea.

10.6 Hazardous decomposition products

When heated to decomp it emits very toxic fumes of NOx and Cl-.

11.Toxicological information

Acute toxicity

• Oral: LD50 Rat oral > 4640 mg/kg
• Inhalation: no data available
• Dermal: LD50 Rabbit percutaneous >2000 mg/kg

Skin corrosion/irritation

no data available

Serious eye damage/irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available

Carcinogenicity

Cancer Classification: Group E Evidence of Non-carcinogenicity for humans

Reproductive toxicity

no data available

STOT-single exposure

no data available

STOT-repeated exposure

no data available

Aspiration hazard

no data available

12.Ecological information

12.1 Toxicity

• Toxicity to fish: LC50; Species: /Oncorhynchus mykiss/ (Rainbow trout) juvenile; Concentration: >150 mg/L for 96 hr /Conditions of bioassay not specified
• Toxicity to daphnia and other aquatic invertebrates: EC50; Species: Daphnia magna (Water Flea) age <24 hr; Conditions: freshwater, static; Concentration: 1.5 ug/L for 48 hr (95% confidence interval: 0.8-2.9 ug/L); Effect: intoxication, immobilization
• Toxicity to algae: EC50; Species: Pseudokirchneriella subcapitata (Green Algae); Conditions: freshwater, static; Concentration: >124000 ug/L for 72 hr; Effect: population abundance /79.4% purity
• Toxicity to microorganisms: no data available

12.2 Persistence and degradability

AEROBIC: The ultimate biodegradation rate constant of diflubenzuron at 28°C was measured to be 0.037 day-1 in a sandy loam and 0.026 day-1 in muck soil(1) which correspond to half-lives of about 19 and 27 days, respectively(SRC). In the same study, 80-87% diflubenzuron (initial concentration of 10 ppm) remained in sterile soil after 12 weeks; therefore, soil microorganisms play a major role in the disappearance of diflubenzuron(1). Based on several screening tests, the biodegradation half-life averaged 2.4 days using freshwater sediment and 15 days in sterile freshwater sediment(2). Biodegradation half-lives averaged 14 and 32 days using marine-sediment and marine-water, respectively(2). There were no differences in the disappearance of diflubenzuron from sewage water, whether boiled or unboiled; a 14-15% reduction from 0.1 ppm initial concentration was observed immediately following treatment. Reductions of 30% at 6 hr and 42% at 24 hr were probably due to adsorption(3). When applied to a sandy loam soil under aerobic conditions at 24°C, diflubenzuron had half-lives ranging from 2-14 days (depending on soil texture) with the major degradates being 4-chlorophenyl urea and CO2(4); three minor degradates were 2,6-difluorobenzoic acid, 2,6-difluorobenzamide, and 4-chloroaniline(4).

12.3 Bioaccumulative potential

Reported bioconcentration factors for diflubenzuron in bluegill sunfish (Lepomis macrochirus) ranged from 34 to 200 for fillet and 78 to 360 for whole fish(1). According to a classification scheme(2), these BCF ranges suggest the potential for bioconcentration in aquatic organisms is moderate to high. Diflubenzuron depurates rapidly in fish tissue(1); the depuration rate indicates a rapid decrease (99%) of accumulated residues in tissue during a 14-day depuration period.

12.4 Mobility in soil

Diflubenzuron has reported Koc values of 6,790 and 10,600(1). According to a classification scheme(2), these Koc values suggest that diflubenzuron is expected to be immobile in soil. Binding to soil is an important transport process for diflubenzuron based on soil Kd values for sand clay, silty clay loam, silt loam, sand loam, sandy clay loam, clay, clay hydrosoil, and peat hydrosoil of 40, 40, 20, 25, 130, 110, 150, and 3500, respectively(3). Diflubenzuron is classified as relatively immobile in soil based on Rf values were 0.01, 0.07, 0.14, and 0.34 for silty clay loam, clay loam, and two sand loam soils, respectively(3). In field tests, diflubenzuron was not detectable below the 0-15 cm soil depth segment over a 60-day period(3). In water tank studies, diflubenzuron adsorbed to sediment showed no detectable diffusion from the sediment to water over a 204-day observation period(4).

12.5 Other adverse effects

no data available

13.Disposal considerations

13.1 Disposal methods

Product

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Contaminated packaging

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

14.Transport information

14.1 UN Number

14.2 UN Proper Shipping Name

14.3 Transport hazard class(es)

14.4 Packing group, if applicable

14.5 Environmental hazards

14.6 Special precautions for user

no data available

14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

no data available

15.Regulatory information

15.1 Safety, health and environmental regulations specific for the product in question

16.Other information

Information on revision

Abbreviations and acronyms

• CAS: Chemical Abstracts Service
• ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
• RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
• IMDG: International Maritime Dangerous Goods
• IATA: International Air Transportation Association
• TWA: Time Weighted Average
• STEL: Short term exposure limit
• LC50: Lethal Concentration 50%
• LD50: Lethal Dose 50%
• EC50: Effective Concentration 50%

References

• IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
• HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
• IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
• eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
• CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
• ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
• ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
• Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
• ECHA - European Chemicals Agency, website: https://echa.europa.eu/

Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.