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Compound | tigecycline | ||||
---|---|---|---|---|---|
CAS No. | 220620-09-7 | Catalog No. | XMZX-W7680 | Brand | |
Purity | 99% | Packing | 25kg/DRUMS | Grade | |
Lead Time | 3Day (s) | Origin | Loading Port | China,Xiamen,Siming District |
Boiling Point | 890.922ºC at 760 mmHg |
---|---|
Appearance & Physical State | Powder |
Flash Point | 492.612ºC |
Refractive Index | 1.675 |
Density | 1.455 g/cm3 |
Vapor Pressure | 0mmHg at 25°C |
Uses antineoplastic
Uses Tigecycline is a semi-synthetic tetracycline prepared by the introduction of a tert-butylaminoacetamido group into a previously unexplored and un-substituted region of existing tetracyclines. Like other tetracyclines, tigecycline acts by reversibly binding to the 30S ribosomal subunit and inhibits protein translation by blocking entry of aminoacyl-tRNA into the ribosome A site. The enhanced activity can be attributed to stronger binding affinity, thus minimising the impact of existing mechanisms of resistance. Tigecycline is regarded as the first of a new class of glycylcyline antibiotics. Critical comparison to the tetracycline class appears to be lacking in the literature.
Uses A broad spectrum glycylcycline antibiotic
Uses A glycylcycline antibiotic, used to treat infection by drug resistant bacteria such as Staphylococcus aureus (Staph aureus) and Acinetobacter baumannii.
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