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Compound | 6-[(R)-amino-(4-chlorophenyl)-(3-methylimidazol-4-yl)methyl]-4-(3-chlorophenyl)-1-methylquinolin-2-one | ||||
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CAS No. | 192185-72-1 | Catalog No. | XMZX-W6824 | Brand | |
Purity | 99% | Packing | 25kg/DRUMS | Grade | |
Lead Time | 3Day (s) | Origin | Loading Port | China,Xiamen,Siming District |
Boiling Point | 681.7ºC at 760mmHg |
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Appearance & Physical State | Off-white to pale beige solid |
Flash Point | 366.1ºC |
Refractive Index | 1.671 |
Density | 1.33g/cm3 |
Melting Point | 211-213ºC (dec.) |
Vapor Pressure | 1.94E-18mmHg at 25°C |
Uses A farnesyltransferase inhibitor. Sensitizes human multiple myeloma cell to proteasome inhibition by blocking degradation of bortezomib(B675700)-induced aggresomes. Also shown to inhibit the growth of myeloid leukemia cell lines and primary leukemia cells by inducing apoptosis and cell-cycle blockage when combined with rapamycin(R124000).
CAS No : 192185-72-1
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6-[amino-(4-chlorophenyl)-(3-methylimidazol-4-yl)methyl]-4-(3-chlorophenyl)-1-methylquinolin-2-one
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