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Compound | (R,R)-2-amino-1-(4-nitrophenyl)propane-1,3-diol | ||||
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CAS No. | 716-61-0 | Catalog No. | XMZX-W16943 | Brand | |
Purity | 99% | Packing | 25kg/DRUMS | Grade | |
Lead Time | 3Day (s) | Origin | Loading Port | China,Xiamen,Siming District |
Boiling Point | 451.9ºC at 760 mmHg |
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Storage Condition | -20ºC |
Appearance & Physical State | light yellow powder |
Flash Point | 227.1ºC |
Density | 1.41 g/cm3 |
Melting Point | 163-165ºC |
Uses D-threo-(-)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol is an impurity of Chloramphenicol (C325030), a broad spectrum antibiotic agent obtained from cultures of the soil bacterium Streptomyces venezuel ae.
Uses Chloramphenicol base is the parent 4-nitrophenylpropylamine formed by the hydrolysis of the dichloroacetamide of chloramphenicol and is a degradation product commonly encountered with commercial production of chloramphenicol. Chloramphenicol base has no antibiotic activity but has played an integral role in the synthesis and SAR of new generation antibiotics, notably thiamphenicol and experimental analogues, bromamphenicol and methamphenicol.
Uses
(1R,2R)-(-)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol may be used in the preparation of (1R,2R)-(-)-2-dimethylamino-1-(4-nitrophenyl)-1,3-propanediol via N,N-dimethylation. It may also be used as a starting material to synthesize (1R,2R)-1,3-diacetoxy-1-(4-nitrophenyl)-2-propylisothioeyanate [(R,R)-DANI].
(R,R)-2-amino-1-(4-nitrophenyl)propane-1,3-diol
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