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Simagchem Corp.

Simagchem Corp.

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China Fujian Xiamen
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13806087780
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Catalog No. : XMZX-W16136

forskolin

  • 66575-29-9
  • 25kg/DRUMS
  • 99%
  • China,Xiamen,Siming District
  • 3Day (s)
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  • Product Details & Description

Product Info

Compound FORSKOLIN
CAS No. 66575-29-9 Catalog No. XMZX-W16136 Brand
Purity 99% Packing 25kg/DRUMS Grade
Lead Time 3Day (s) Origin Loading Port China,Xiamen,Siming District

PropertiesMore

Boiling Point 519.9ºC at 760 mmHg
Storage Condition -20ºC
Appearance & Physical State Colorless Crystalline Solid
Flash Point 171.8ºC
Refractive Index 1.551
Density 1.23 g/cm3
Melting Point 282-232ºC

Description

ses Forskolin is a diterpene isolated from Coleus forskohlii, possessing vasodilating and cardiostimulatory properties. Forskolin resensitizes cell receptors by activating the enzyme adenylyl cyclase and increasing the intracellular levels of cAMP.

Uses glucocorticoid, antiinflammatory

Uses adenylate cyclase activator, antiglaucoma, hypotensive, vasodilator

Uses Cyclic AMP (cAMP) is an important signal carrier necessary for the proper biological response of cells to hormones, neurotransmitters, and other extracellular signals Forskolin is a naturally occurring diterpene that is produced by the Indian Coleus plant (C. forskohlii). It directly activates adenylyl cyclase through its catalytic subunit and is commonly used to raise levels of cAMP in a wide variety of intact cells and tissue preparations. Forskolin binds to adenylyl cyclase in membranes from stably transfected Sf9 cells expressing type 1 adenylyl cyclase with an IC50 value of 41 nM and demonstrates an EC50 value of 0.5 μM in an activation assay assessing formation of cAMP from ATP. Forskolin also interacts with glucose transporters and certain ion channels and has been used for examining adenylyl cyclase expression, regulation, and G protein signaling.[Cayman Chemical]

Uses An adenylate cyclase activator and MAP kinase inhibitor

Uses In purification of adenylate cyclase.

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Product

forskolin

Cas No

66575-29-9

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