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Simagchem Corp.

Simagchem Corp.

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China Fujian Xiamen
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13806087780
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Catalog No. : XMZX-W15451

2-Chloro-5-Fluoropyrimidine

  • 62802-42-0
  • 25kg/DRUMS
  • 99%
  • China,Xiamen,Siming District
  • 3Day (s)
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  • Product Details & Description

Product Info

Compound 2-Chloro-5-fluoropyrimidine
CAS No. 62802-42-0 Catalog No. XMZX-W15451 Brand
Purity 99% Packing 25kg/DRUMS Grade
Lead Time 3Day (s) Origin Loading Port China,Xiamen,Siming District

PropertiesMore

Boiling Point 149.0-162.0ºC
Appearance & Physical State Colorless to light yellow liquid
Flash Point 150 °F
Refractive Index 1.503
Density 1.073

Description

Uses 2-Chloro-5-fluoropyrimidine is used to prepare 2,4-disubstituted-5-fluoropyrimidine , which is a biologically active molecule seen in anticancer agents like 5-fluorouracil.

Uses

2-Chloro-5-fluoropyrimidine can be used as a starting material for the preparation of:

5-fluoro-2-amino pyrimidines by reacting with various amines in the presence of K2CO3, via C-N bond forming reaction.

2-chloro-5-(5-fluoropyrimidin-2-yl)benzoic acid, an intermediate, which is used in the synthesis of benzamide scaffolds as potent antagonists against P2X7 receptors.

5-fluoro-2-cyano pyrimidine, a key intermediate used for the synthesis of 5-chloro-N-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]-N-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine, as a potent inhibitor of the JAK2 kinase.

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Product

2-Chloro-5-Fluoropyrimidine

Cas No

62802-42-0

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