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Simagchem Corp.

Simagchem Corp.

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China Fujian Xiamen
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13806087780
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Catalog No. : XMZX-W4585

2-Iodoacetamide

  • 144-48-9
  • 25kg/DRUMS
  • 99%
  • China,Xiamen,Siming District
  • 3Day (s)
Packing :
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Product Info

Compound 2-Iodoacetamide
CAS No. 144-48-9 Catalog No. XMZX-W4585 Brand
Purity 99% Packing 25kg/DRUMS Grade
Lead Time 3Day (s) Origin Loading Port China,Xiamen,Siming District

PropertiesMore

Boiling Point 297.1ºC at 760 mmHg
Stability Stable, but light sensitive. Incompatible with strong oxidizing agents, strong bases, reducing agents, acids.
Storage Condition 2-8ºC
Appearance & Physical State crystalline
Water Solubility slightly soluble
Flash Point 133.5ºC
Density 2.278 g/cm3
Melting Point 92-95ºC

Description

Uses Alkylating agent used in peptide mapping because it covalently binds with the thiols in cysteine to prevent disulfide bond formation2-Iodoacetamide is used as an electrophile for covalent modification of nucleophilic residues on proteins such as cysteine, methionine and histidine. It is used to bind with thiol group of cysteine, thereby it protects the formation disulfide bonds. It is involved as an inhibitor of deubiquitinase enzymes (DUBs). Further, it acts as an alkylating sulfhydryl reagent.

Uses

Alkylating reagent for cysteine residues in peptide sequencing. By virtue of reaction with cysteine, it is an irreversible inhibitor of enzymes with cysteine at the active site. It reacts much more slowly with histidine residues, but that activity is responsible for inhibition of ribonuclease.

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Product

2-Iodoacetamide

Cas No

144-48-9

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