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Compound | (2R,3S)-N-Benzoyl-3-phenyl Isoserine | ||||
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CAS No. | 132201-33-3 | Catalog No. | XMZX-W3524 | Brand | |
Purity | 99% | Packing | 25kg/DRUMS | Grade | |
Lead Time | 3Day (s) | Origin | Loading Port | China,Xiamen,Siming District |
Boiling Point | 580.7ºC at 760 mmHg |
---|---|
Appearance & Physical State | white powder |
Flash Point | 305ºC |
Refractive Index | 1.625 |
Density | 1.316g/cm3 |
Melting Point | 169 - 172ºC |
Vapor Pressure | 2.51E-14mmHg at 25°C |
Uses (2R,3S)-N-Benzoyl-3-phenylisoserine is an intermediate in the preparation of potent anticancer drug Paclitaxel (P132500) used to study the location of the binding sites. (2R,3S)-N-Benzoyl-3-phenylisoserine shows cytotoxic, antiviral and immunomodulatory activity.
Uses
The presence of this chiral side chain has proven to be essential for the biological activity of taxol, one of the most promising anticancer agents being investigated. The challenging synthesis of taxol has stimulated interest in the attachment of the C-13 side chain to naturally derived taxanes like baccatin III.
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