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Compound | N-(4-((6-Methoxy-7-(3-Morpholinopropoxy)quinazolin-4-yl)aMino)phenyl)benzaMide | ||||
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CAS No. | 331771-20-1 | Catalog No. | XMZX-W10036 | Brand | |
Purity | 99% | Packing | 25kg/DRUMS | Grade | |
Lead Time | 3Day (s) | Origin | Loading Port |
Boiling Point | 639.671ºC at 760 mmHg |
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Appearance & Physical State | Pale yellow solid |
Flash Point | 340.661ºC |
Refractive Index | 1.664 |
Density | 1.282 g/cm3 |
Melting Point | 117-120ºC |
Chemical Properties Pale Yellow Solid
Uses It is a potent and selective inhibitor of Aurora B kinase. Cells treated with ZM-447439 progress through interphase, enter mitosis and assemble bipolar spindles but chromosome alignment, segregation a nd cytokinesis all fail. It induces apoptosos in Hep2 cancer cells and in acute myeloid leukemia cell lines but its propensity to induce polyploidy does not inevitably result in apoptosis.
N-(4-((6-Methoxy-7-(3-Morpholinopropoxy)quinazolin-4-yl)aMino)phenyl)benzaMide
CAS No : 331771-20-1