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Beijing Anbiqi Biotechnology Co., Ltd.

Beijing Anbiqi Biotechnology Co., Ltd.

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China Beijing Tongzhou
contact@abace-biology.com
010572638

Catalog No. : CEI-0504

Chidamide impurity

  • 743420-02-2
  • 100g
  • 85%
  • 7Day (s)
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Compound Chidamide impurity
CAS No. 743420-02-2 Catalog No. CEI-0504 Brand
Purity 85% Packing 100g Grade
Lead Time 7Day (s) Origin Loading Port

Description

An enzyme inhibitor is a molecule, which binds to enzyme and subsequently stops a substrate from entering the active site of enzyme and/or hinders the catalysis of enzyme.Cell-permeable. A new benzamide class of histone deacetylase (HDAC) inhibitor with marked anti-tumor activity. It increases histone H3 acetylation levels in LoVo and HT29 colon cancer cells at concentrations as low as 4 µM. Additionally, chidamide affects the activation of oncogenic signaling kinases by dose-dependently reducing phosphorylated Akt, mTOR, p70S6k, Raf, and Erk1/2 protein expression in colon cancer cells. *Targets: HDAC *Chemical Name: N-​(2-​amino-​5-​fluorophenyl)-​4-​[[[1-​oxo-​3-​(3-​pyridinyl)-​2-​propen-​1-​yl]amino]methyl]-​benzamide

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Chidamide impurity

Cas No

743420-02-2

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