tadalafil171596-29-5,Purity_HANGZHOU DINGYAN CHEM CO.,LTD

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Purity :

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CAS NO.: 171596-29-5

Purity :

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tadalafil

CAS No : 171596-29-5
Packing : 25kg
Brand :
Purity :
Loading Port :
Lead Time :

Packing :

25kg

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Product Details & Description
COA

Product Info

Compound	Tildenafil
CAS No.	171596-29-5	Catalog No.		Brand
Purity		Packing	25kg	Grade
Lead Time		Origin		Loading Port

PropertiesMore

Boiling Point	679.1ºC at 760 mmHg
Appearance & Physical State	Off-White Cyrstalline Solid
Flash Point	364.5ºC
Refractive Index	1.705
Density	1.51 g/cm3
Melting Point	298-300ºC
Vapor Pressure	5.29E-13mmHg at 25°C

Description

Mechanism of action: Erectile dysfunction: Tadalafil and sildenafil belong to the same selective type 5 phosphodiesterase (PDE5), but their structure is different from that of the latter, and a high-fat diet does not interfere with their absorption. Under sexual stimulation, nitric oxide synthase (NOS) in penile nerve endings and vascular endothelial cells catalyzes substrate L-arginine to synthesize nitric oxide (NO). NO activates guanylate cyclase, which converts guanosine triphosphate into cyclic guanosine phosphate (cGMP), thereby activating cyclic guanosine phosphate dependent protein kinase, resulting in a decrease in the concentration of calcium ions in smooth Chemicalbook muscle cells, resulting in relaxation of the smooth muscle of the corpus cavernosum and erection. Phosphodiesterase type 5 (PDE5) degrades cGMP into an inactive product, causing the penis to enter a weak state. By inhibiting PDE5 degradation, Tadanafil leads to cGMP accumulation, which relaxes the smooth muscle of the cavernous body of the penis and leads to penile erection. Since nitrates are NO donors, the combination with tadanafil can significantly increase the level of cGMP and lead to severe hypotension, therefore, clinical contraindication of the two.

No.	Description	Update Time	Operation
1	COA	2024/06/07	Download

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Product Name	Purity	Packing	Lead Time	Country	Store Name	Details
Tadalafil	98%	1kg	7Day (s)	China,Jiangsu	Changzhou Xinxinglian Biotechnology Co., Ltd.	Request For Quotation
Tadalafil	98%	10g	3Day (s)	China,Zhejiang	Wenzhou Win-Win Chemical Co., Ltd.	Request For Quotation
Tildenafil	＞97%	1kg	7Day (s)	China,Zhejiang	Hangzhou J&H Chemical Co., Ltd.	Request For Quotation
Tildenafil	99%	1kg	14Day (s)	China,Shaanxi	Baoji Guokang Bio-Technology Co., Ltd	Request For Quotation
Cialis	99%	1kg	7Day (s)	China,Zhejiang	Skyrun Industrial Co., Limited	Request For Quotation
Tadalafil	98%	1kg	2-3Day (s)	China,Henan	Henan Coreychem Co.,Ltd	Request For Quotation
Tildenafil	97%	250mg,1g	1Week (s)	China,Shanghai	Shanghai Jizhi Biochemical Technology Co., Ltd.	Request For Quotation
Tildenafil	98%	1kg,1吨	7Day (s)	China,Zhejiang	Hangzhou DayangChem Co., Ltd	Request For Quotation
Cialis	98	100g	IN STOCK	China,Jiangsu	Jiangsu Bida Pharmaceutical Technology Co., Ltd.	Request For Quotation
Tildenafil	98%	100kg,1kg	7Day (s)	China,Zhejiang	Hangzhou Shangjie Chemical Co., Ltd.	Request For Quotation

Product Name

Purity

Packing

Lead Time

Country

Store Name

Details

Tadalafil

98%

1kg

7Day (s)

China,Jiangsu