18-methoxy-18-oxooctadecanoic acid
CAS NO.: 72849-35-5
Purity :95%
1-((9H-fluoren-9-yl)methyl) 2-(tert-butyl) hydrazine-1,2-dicarboxylate
CAS NO.: 936015-89-3
Purity :95%
Compound | (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)pent-4-enoic acid | ||||
---|---|---|---|---|---|
CAS No. | 146549-21-5 | Catalog No. | 8303107 | Brand | SYNTIDES |
Purity | 95% by HPLC (TLC) | Packing | 5g | Grade | |
Lead Time | Origin | Loading Port |
Boiling Point | 563ºC at 760 mmHg |
---|---|
Storage Condition | 2-8ºC |
Appearance & Physical State | White powder |
Flash Point | 294.3ºC |
Refractive Index | 1.602 |
Density | 1.245g/cm3 |
Melting Point | 137.1ºC |
Vapor Pressure | 1.64E-13mmHg at 25°C |
(S)-N-Fmoc-allyl-glycine
Item Number :8303107CAS Registry Number :146549-21-5Synonyms :(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)pent-4-enoic acid,MDL Number :MFCD01311749Molecular FormulaC20H19NO4Relative Moleucular Mass337.37Storage Condition
Usage: For Scientific Research Use Only, Not for Human Use.
Product Name:
Fmoc-L-Allyglycine
Purity:
95% by HPLC (TLC)
Appearance:
White Powder
Solubility:
No data available
Melting Point:
No data available
Compound ID:
2734457
Description:
Conformationally stabilized α-helical peptides are capable of inhibiting disease-relevant intracellular or extracellular protein-protein interactions in vivo. In order to improve the enzymatic stability of peptides, ruthenium-catalysed ring closing metathesis was used to generate a macrocyclic peptide using allylglycine residues as handles for ring formation.Preparation of several side chain length variants of glutamic acid is achieved via olefin cross metathesis of allyl glycine derivatives.
References:
Org Lett. 2014 Jul 18;16(14):3712-5. Biomacromolecules. 2014 Mar 10;15(3):978-84. Bioorg Med Chem. 2011 Jun 1;19(11):3549-57. Brain Res Bull. 2010 Mar 16; 81(4-5):416-23. Journal of Molecular Graphics and Modelling.olume 26, Issue 7, April 2008, Pages 1082–1090.Br J Pharmacol. 1973 Sep; 49(1):52-63.
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