sodium nitrite

Description

Sodium nitrite is the inorganic compound with the chemical formula NaNO2. It is a white to slightly yellowish crystalline powder that is very soluble in water and is hygroscopic. It is a useful precursor to a variety of organic compounds, such as pharmaceuticals, dyes, and pesticides, but it is probably best known as a food additive to prevent botulism.
It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system.

Basic Info

Chemical Name	sodium nitrite
Synonyms	Sodium nitrite solution; SODIUM NITRITE; Caswell No. 782; Sodium,nitrite; sodium nitrile; Filmerine; Erinitrit; Nitrous acid,sodium salt; Diazotizing salts; Nitrite,sodium; Anti-rust; Expand
CAS No.	7632-00-0
Molecular Formula	NNaO2
Molecular Weight	68.99530
PSA	52.49000
LogP	0.25060

Numbering system

UNII	M0KG633D4F

Properties

Appearance & Physical State	white to off-white powder
Density	2.168
Boiling Point	320ºC
Melting Point	271ºC
Water Solubility	820 g/L (20 ºC)
Stability	Stable. Incompatible with reducing agents, strong oxidizing agents, organics and other flammable materials, finely powdered metals. Contact with combustible material may lead to fire. Hygroscopic.
Storage Condition	2-8ºC

Safety Info

RTECS	RA1225000
Hazard Class	5.1
Safety Statements	S45-S61
HS Code	2834299090
WGK Germany	3
Packing Group	III
RIDADR	UN 3219
Risk Statements	R25; R50; R8
Hazard Codes	T
Hazard Declaration	H272; H301; H319; H400
Symbol	GHS03, GHS06, GHS09
Caution Statement	P210; P220; P221; P305 + P351 + P338; P370 + P378
Signal Word	Danger

Synthesis Route

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sodium hydroxide

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sodium carbonate

: 7632-00-0
sodium nitrite

Detail>>

More

MSDS

Total 2 Documents >>

SDS 1.0 Expand

SDS 1.0

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1.Identification

1.1 GHS Product identifier

Product name	sodium nitrite

1.2 Other means of identification

Product number	-
Other names	Sodium,nitrite

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

Company	MOLBASE (Shanghai) Biotechnology Co., Ltd.
Address	Floor 4 & 5, Building 12, No. 1001 North Qinzhou Road, Xuhui District, Shanghai, China
Telephone	+86(21)64956998
Fax	+86(21)54365166

1.5 Emergency phone number

Emergency phone number	+86-400-6021-666
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

2.Hazard identification

2.1 Classification of the substance or mixture

Oxidizing solids, Category 3

Acute toxicity - Oral, Category 3

Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

2.2 GHS label elements, including precautionary statements

Pictogram(s)
Signal word	Danger
Hazard statement(s)	H272 May intensify fire; oxidizer H301 Toxic if swallowed H400 Very toxic to aquatic life
Precautionary statement(s)
Prevention	P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. P220 Keep away from clothing and other combustible materials. P280 Wear protective gloves/protective clothing/eye protection/face protection. P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P273 Avoid release to the environment.
Response	P370+P378 In case of fire: Use ... to extinguish. P301+P310 IF SWALLOWED: Immediately call a POISON CENTER/doctor/… P321 Specific treatment (see ... on this label). P330 Rinse mouth. P391 Collect spillage.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to ...

2.3 Other hazards which do not result in classification

none

3.Composition/information on ingredients

3.1 Substances

Chemical name	Common names and synonyms	CAS number	EC number	Concentration
sodium nitrite	sodium nitrite	7632-00-0	none	100%

4.First-aid measures

4.1 Description of necessary first-aid measures

General advice

Consult a physician. Show this safety data sheet to the doctor in attendance.

If inhaled

If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.

In case of skin contact

Wash off with soap and plenty of water. Consult a physician.

In case of eye contact

Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.

If swallowed

Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

4.2 Most important symptoms/effects, acute and delayed

no data available

4.3 Indication of immediate medical attention and special treatment needed, if necessary

no data available

5.Fire-fighting measures

5.1 Extinguishing media

Suitable extinguishing media

Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

5.2 Specific hazards arising from the chemical

no data available

5.3 Special protective actions for fire-fighters

Wear self-contained breathing apparatus for firefighting if necessary.

6.Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.

6.2 Environmental precautions

Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.

6.3 Methods and materials for containment and cleaning up

Pick up and arrange disposal. Sweep up and shovel. Keep in suitable, closed containers for disposal.

7.Handling and storage

7.1 Precautions for safe handling

Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

8.Exposure controls/personal protection

8.1 Control parameters

Occupational Exposure limit values

no data available

Biological limit values

no data available

8.2 Appropriate engineering controls

Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

8.3 Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

Respiratory protection

Wear dust mask when handling large quantities.

Thermal hazards

no data available

9.Physical and chemical properties

Physical state	white to off-white powder
Colour	no data available
Odour	no data available
Melting point/ freezing point	271ºC
Boiling point or initial boiling point and boiling range	320ºC
Flammability	no data available
Lower and upper explosion limit / flammability limit	no data available
Flash point	no data available
Auto-ignition temperature	490°C
Decomposition temperature	no data available
pH	no data available
Kinematic viscosity	no data available
Solubility	In water:820 g/L (20 ºC)
Partition coefficient n-octanol/water (log value)	no data available
Vapour pressure	no data available
Density and/or relative density	2.168
Relative vapour density	no data available
Particle characteristics	no data available

10.Stability and reactivity

10.1 Reactivity

no data available

10.2 Chemical stability

Stable under recommended storage conditions.

10.3 Possibility of hazardous reactions

no data available

10.4 Conditions to avoid

no data available

10.5 Incompatible materials

no data available

10.6 Hazardous decomposition products

no data available

11.Toxicological information

Acute toxicity

Oral: no data available
Inhalation: no data available
Dermal: no data available

Skin corrosion/irritation

no data available

Serious eye damage/irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available

Carcinogenicity

no data available

Reproductive toxicity

no data available

STOT-single exposure

no data available

STOT-repeated exposure

no data available

Aspiration hazard

no data available

12.Ecological information

12.1 Toxicity

Toxicity to fish: no data available
Toxicity to daphnia and other aquatic invertebrates: no data available
Toxicity to algae: no data available
Toxicity to microorganisms: no data available

12.2 Persistence and degradability

no data available

12.3 Bioaccumulative potential

no data available

12.4 Mobility in soil

no data available

12.5 Other adverse effects

no data available

13.Disposal considerations

13.1 Disposal methods

Product

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Contaminated packaging

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

14.Transport information

14.1 UN Number

ADR/RID: UN1500

IMDG: UN1500

IATA: UN1500

14.2 UN Proper Shipping Name

ADR/RID: SODIUM NITRITE

IMDG: SODIUM NITRITE

IATA: SODIUM NITRITE

14.3 Transport hazard class(es)

ADR/RID: 6.1

IMDG: 6.1

IATA: 6.1

14.4 Packing group, if applicable

ADR/RID: III

IMDG: III

IATA: III

14.5 Environmental hazards

ADR/RID: yes

IMDG: yes

IATA: yes

14.6 Special precautions for user

no data available

14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

no data available

15.Regulatory information

15.1 Safety, health and environmental regulations specific for the product in question

Chemical name	Common names and synonyms	CAS number	EC number
sodium nitrite	sodium nitrite	7632-00-0	none
European Inventory of Existing Commercial Chemical Substances (EINECS)			Listed.
EC Inventory			Listed.
United States Toxic Substances Control Act (TSCA) Inventory			Listed.
China Catalog of Hazardous chemicals 2015			Listed.
New Zealand Inventory of Chemicals (NZIoC)			Listed.
Philippines Inventory of Chemicals and Chemical Substances (PICCS)			Listed.
Vietnam National Chemical Inventory			Listed.
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC)			Listed.

16.Other information

Information on revision

Creation Date	Aug 16, 2017
Revision Date	Aug 16, 2017

Abbreviations and acronyms

CAS: Chemical Abstracts Service
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
IMDG: International Maritime Dangerous Goods
IATA: International Air Transportation Association
TWA: Time Weighted Average
STEL: Short term exposure limit
LC50: Lethal Concentration 50%
LD50: Lethal Dose 50%
EC50: Effective Concentration 50%

References

IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
ECHA - European Chemicals Agency, website: https://echa.europa.eu/

Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.

MSDS Expand: MSDS
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Section 1: Product Identification
   Chemical Name:       Sodium nitrite, 97+% (ACS)
   CAS Registry Number:       7632-00-0
   Formula:       NaNO2
   EINECS Number:       231-555-9
   Chemical Family:       inorganic compound
   Synonym:       Nitrous acid, sodium salt

Section 2: Composition and Information on Ingredients
   Ingredient       CAS Number       Percent       ACGIH (TWA)       OSHA (PEL)
   Title compound       7632-00-0       100%       no data       no data

Section 3: Hazards Identification
   Irritating to eyes, skin, and respiratory tract. Toxic by inhalation and if swallowed. May cause heritable genetic
   Emergency Overview:
   damage, harm to the unborn child, and impair fertility.
   Primary Routes of Exposure:       Ingestion, inhalation, skin, eyes.
   Eye Contact:       Causes irritation, redness and pain.
   Skin Contact:       Causes irritation, redness and pain. May be absorbed through the skin.
   Inhalation:       Toxic. Causes irritation to the respiratory tract, and in large amounts, poisoning.
   Toxic. Ingestion of as little as 1/2 ounce may cause nitrite poisoning including intense cyanosis, nausea,
   Ingestion:
   dizziness, vomiting, collapse, coma, and death.
   Irritating to eyes, skin, and respiratory tract. Toxic by inhalation and if swallowed. Nitrite poisoning may cause
   Acute Health Affects:       cyanosis, nausea, dizziness, vomiting, collapse, rapid heart beat, irregular breathing, coma, convulsions,
   circulatory collapse and death. May cause harm to the unborn child.
   Chronic Health Affects:       May cause heritable genetic damage and impair fertility.
   NTP:       No
   IARC:       No
   OSHA:       No

SECTION 4: First Aid Measures
   Immediately flush the eyes with copious amounts of water for at least 10-15 minutes. A victim may need
   Eye Exposure:
   assistance in keeping their eye lids open. Get immediate medical attention.
   Wash the affected area immediately with water. Remove contaminated clothing if necessary. Seek medical
   Skin Exposure:
   assistance if irritation persists.
   Remove the victim to fresh air. Closely monitor the victim for signs of respiratory problems, such as difficulty
   Inhalation:
   in breathing, coughing, wheezing, or pain. In such cases seek immediate medical assistance.
   Seek medical attention immediately. Keep the victim calm. Give the victim water (only if conscious). Induce
   Ingestion:
   vomiting only if directed by medical personnel.

SECTION 5: Fire Fighting Measures
   Flash Point:       no data
   Autoignition Temperature:       no data
   Explosion Limits:       no data
   Extinguishing Medium:       carbon dioxide or dry powder
   If this product is involved in a fire, fire fighters should be equipped with a NIOSH approved positive pressure
   Special Fire Fighting Procedures:
   self- contained breathing apparatus and full protective clothing.
   Hazardous Combustion and       If involved in a fire, this material may emit toxic and corrosive fumes of nitrogen oxides.
   Decomposion Products:
   Unusual Fire or Explosion Hazards: Metal nitrites are oxidizers. Contact with combustible materials can lead to fires and/or explosions.

SECTION 6: Accidental Release Measures
   Spill and Leak Procedures:       Do not mix spilled powder with any combustible materials. Sweep up the solid and dilute with water.

SECTION 7: Handling and Storage
   Handling and Storage:       Store in a cool, dry place in a tightly sealed container.

SECTION 8: Exposure Controls and Personal Protection
   Eye Protection:       Always wear approved safety glasses when handling a chemical substance in the laboratory.
   Skin Protection:       Wear protective clothing and gloves. Consult with glove manufacturer to determine the proper type of glove.
   Ventilation:       Handle the material in an efficient fume hood.
   If ventilation is not available a respirator should be worn. The use of respirators requires a Respiratory
   Respirator:
   Protection Program to be in compliance with 29 CFR 1910.134.
   Ventilation:       Handle the material in an efficient fume hood.
   Additional Protection:       No additional protection required.

SECTION 9: Physical and Chemical Properties
   Color and Form:       white powder
   Molecular Weight:       69
   Melting Point:       271°
   Boiling Point:       320°C dec.
   Vapor Pressure:       not applicable
   Specific Gravity:       2.168
   Odor:       none
   Solubility in Water:

SECTION 10: Stability and Reactivity
   Stability:       hygroscopic
   Hazardous Polymerization:       No hazardous polymerization
   Conditions to Avoid:       may burst into flame or explode in contact with organic matter in the presence of heat or friction.
   ammonium salts, cellulose, cyanides, lithium, potassium plus ammonia, sodium thiosulfate, aminoguanide
   Incompatibility:
   salts, butadiene, reluctant.
   Decomposition Products:       nitrogen oxides and sodium oxide.

SECTION 11: Toxicological Information
   Administration into the eye (rabbit); Standard Draize test: 500 mg/24H. Oral (human); TDLo: 14 mg/kg. Oral
   (human-man); LDLo: 321 mg/kg. Oral (human-man); TDLo: 1714 ug/kg/70M. Oral (human); LDLo: 71 mg/kg.
   RTECS Data:       Oral (human-child); LDLo: 22 mg/kg. Oral (rat); LD50: 180 mg/kg. Inhalation (rat); LC50: 5500 ug/m3/4H.
   Subcutaneous (rat); LD50: 96600 ug/kg. Intravenous (rat); LD50: 65 mg/kg. Oral (rat); TDLo: 180 mg/kg/8D-I.
   Oral (rat); TDLo: 2190 gm/kg/2Y-C. Oral (rat); TDLo: 660 mg/kg. Oral (mouse): TDLo: 480mg/Kg.
   Carcinogenic Effects:       Data available
   Mutagenic Effects:       Mutagen
   Tetratogenic Effects:       Reproductive effector

SECTION 12: Ecological Information
   Ecological Information:       Very toxic to aquatic organisms.

SECTION 13: Disposal Considerations
   Disposal:       Dispose of according to local, state and federal regulations.

SECTION 14: Transportation
   Shipping Name (CFR):       Sodium nitrite
   Hazard Class (CFR):       5.1
   Additional Hazard Class (CFR):       NA
   Packaging Group (CFR):       III
   UN ID Number (CFR):       UN# 1500
   Shipping Name (IATA):       Sodium nitrite
   Hazard Class (IATA):       5.1
   Additional Hazard Class (IATA):       NA
   Packaging Group (IATA):       III
   UN ID Number (IATA):       UN# 1500

SECTION 15: Regulatory Information
   TSCA:       Listed in the TSCA inventory.
   SARA (Title 313):       Title compound regulated under Sec. 313.
   Second Ingredient:       none

SECTION 16 - ADDITIONAL INFORMATION
N/A

Toxicity

Total 115 Documents >>

Exposure Route	Type of Test	Species Observed	Dose/Duration	Toxic Effects
Administration into the eye	Standard Draize test	Rodent - rabbit	500 mg/24H	-
Oral	TDLo - Lowest published toxic dose	Human	14 mg/kg	1.Behavioral-changes in motor activity (specific assay) 2.Vascular-regional or general arteriolar or venous dilation 3.Gastrointestinal-nausea or vomiting
Oral	LDLo - Lowest published lethal dose	Human - man	321 mg/kg	1.Behavioral-coma 2.Lungs, Thorax, or Respiration-cyanosis 3.Blood-methemoglobinemia-carboxyhemoglobin

Precursor

Total 18 Documents >>

: 68378-96-1
Sodium nitrite -15N

: 10102-44-0
nitrogen dioxide

: 497-19-8
sodium carbonate

: 7631-99-4
Sodium nitrate

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Downstream Product

Total 71 Documents >>

: 141341-72-2
2-azido-6-(6-azidopyridin-2-yl)pyridine

: 1423-15-0
1-azido-2,3,4,5,6-pentafluorobenzene

: 34461-00-2
NITROMALONALDEHYDE SODIUM

: 917-61-3
sodium cyanate

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7632-00-0

NNaO2

Description

Basic Info

Chemical Name

Synonyms

CAS No.

Molecular Formula

Molecular Weight

PSA

LogP

Numbering system

Properties

Appearance & Physical State

Density

Boiling Point

Melting Point

Water Solubility

Stability

Storage Condition

Safety Info

RTECS

Hazard Class

Safety Statements

HS Code

WGK Germany

Packing Group

RIDADR

Risk Statements

Hazard Codes

Hazard Declaration

Symbol

Caution Statement

Signal Word

Synthesis Route

MSDS

SDS 1.0

SDS 1.0

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

1.Identification

1.1 GHS Product identifier

1.2 Other means of identification

1.3 Recommended use of the chemical and restrictions on use

1.4 Supplier's details

1.5 Emergency phone number

2.Hazard identification

2.1 Classification of the substance or mixture

2.2 GHS label elements, including precautionary statements

2.3 Other hazards which do not result in classification

3.Composition/information on ingredients

3.1 Substances

4.First-aid measures

4.1 Description of necessary first-aid measures

General advice

If inhaled

In case of skin contact

In case of eye contact

If swallowed

4.2 Most important symptoms/effects, acute and delayed

4.3 Indication of immediate medical attention and special treatment needed, if necessary

5.Fire-fighting measures

5.1 Extinguishing media

Suitable extinguishing media

5.2 Specific hazards arising from the chemical

5.3 Special protective actions for fire-fighters

6.Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

6.2 Environmental precautions

6.3 Methods and materials for containment and cleaning up

7.Handling and storage

7.1 Precautions for safe handling

7.2 Conditions for safe storage, including any incompatibilities

8.Exposure controls/personal protection

8.1 Control parameters

Occupational Exposure limit values

Biological limit values

8.2 Appropriate engineering controls

8.3 Individual protection measures, such as personal protective equipment (PPE)