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telaprevir
CAS No.: 402957-28-2 Formula: C36H53N7O6 Molecular Weight: 679.84900Search Suppliers
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telaprevir
CAS No.:402957-28-2
Formula:C36H53N7O6
Molecular Weight: 679.84900
Description
Telaprevir (VX-950), marketed under the brand names Incivek and Incivo, is a pharmaceutical drug for the treatment of hepatitis C codeveloped by Vertex Pharmaceuticals and Johnson & Johnson. It is a member of a class of antiviral drugs known as protease inhibitors. Specifically, telaprevir inhibits the hepatitis C viral enzyme NS3.4A serine protease. Telaprevir is only indicated for use against hepatitis C genotype 1 viral infections and has not been proven to have an effect on or being safe when used for other genotypes of the virus. The standard therapy of pegylated interferon and ribavirin is less effective on genotype 1.
Basic Info
Chemical Name |
telaprevir |
|---|---|
Synonyms |
|
CAS No. |
402957-28-2 |
Molecular Formula |
C36H53N7O6 |
Molecular Weight |
679.84900 |
PSA |
179.56000 |
LogP |
3.94740 |
Numbering system
| UNII | 655M5O3W0U |
|---|
Properties
Density |
1.25 g/cm3 |
|---|
Synthesis Route
Total 14 Documents >>
MSDS
Total 1 Documents >>Spectrum
Total 1 Documents >>
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- Precursor:
- (S)-N-(1-hydroxypentan-2-yl)formamide methyl (2S)-2-amino-2-cyclohexylacetate pyrazine-2-carboxylic acid (S)-methyl 2-((S)-2-cyclohexyl-2-(pyrazine-2-carboxamido)acetamido)-3,3-dimethylbutanoate (2S)-2-[[(2S)-2-cyclohexyl-2-(pyrazine-2-carbonylamino)acetyl]amino]-3,3-dimethylbutanoic acid (2S)-2-aminopentan-1-ol (1S,3aR,6aS)-ethyl octahydrocyclopenta[c]pyrrole-1-carboxylate (3S)-3-((1S,3aR,6aS)-2-((S)-2-((S)-2-cyclohexyl-2-(pyrazine-2-carboxamido)acetamido)-3,3-dimethylbutanoyl)octahydrocyclopenta[c]pyrrole-1-carboxamido)-1-(cyclopropylamino)-1-oxohexan-2-yl acetate (2S)-2-cyclohexyl-2-(pyrazine-2-carbonylamino)acetic acid methyl (2S)-2-cyclohexyl-2-(pyrazine-2-carbonylamino)acetate
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