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CHUANG HAI BIOTECHNOLOGY CO.,LTD

CHUANG HAI BIOTECHNOLOGY CO.,LTD

Certified Store
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China Hebei Shijiazhuang
info@chuanghaibio.com
+8617633118167
86-0311-81679988

Catalog No. : 6-aminonicotinamide

6-aminonicotinamide (malia@chuanghaibio.com)

  • 329-89-5
  • 1kg/DRUMS
  • CHUANGHAI
  • 99%
  • China,Shanghai,Huangpu
  • 1Day (s)
Packing :
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Price :
US $1.00 /1kg/DRUMS MOQ 1DRUMS,1kg/DRUMS
  • Product Details & Description
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Product Info

Compound 6-aminonicotinamide
CAS No. 329-89-5 Catalog No. 6-aminonicotinamide Brand CHUANGHAI
Purity 99% Packing 1kg/DRUMS Grade
Lead Time 1Day (s) Origin ChinaHebeiShijiazhuang Loading Port China,Shanghai,Huangpu

PropertiesMore

Boiling Point 381.6ºC at 760 mmHg
Appearance & Physical State White crystalline solid
Flash Point 184.6ºC
Refractive Index 1.643
Density 1.323 g/cm3
Melting Point 245-248ºC

Description

Physical & Chemical Property:

6 - Aminonicotinamide (an) is a kind of metabolite resistance, can be used to suppress many cell system of NADPH - producingpentosephosphatepathway (PPP), making it more susceptible to oxidative stress Chemicalbook. 6-Aminonicotinamide is a competitive inhibitor of NADP+ -Dependentenzymetiotide-6-Phosphatedehydrogenase (G6PD) with a Ki value of 0.46μM.

 

Application:

-Aminonicotinamide(100nM;7days)causesasignificantdecreaseinthehumanAR+,hormone-sensitiveprostatecancercelllinesLNCaPandLAPC4,aswellastheCRPC-derivativeC4-2and22Rv1cellmodels.6-Aminonicotinamide(100nM±10nMR1881asindicatedfor3days)increasesbothbasal-andR1881-mediatedROSlevels,suggesting6-Aminonicotinamideisblockingthecells'antioxidantdefense.6-AminonicotinamidealsoincreasesROSlevelsinC4-2cells.

 

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Contact:

Malia

HeBei ChuangHai Biotechnology Co.,Ltd

malia@chuanghaibio.com

Qiaoxi district ,shijiazhuang city,hebei, China.

WhatsApp/Wechat:+8619567966607

www.chuanghaibio.com

No. Description Update Time Operation
1 Company introduction 2023/12/06 Download

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6-aminonicotinamide (malia@chuanghaibio.com)

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329-89-5

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