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Compound | tamibarotene | ||||
---|---|---|---|---|---|
CAS No. | 94497-51-5 | Catalog No. | XMZX-W20115 | Brand | |
Purity | 99% | Packing | 25kg/DRUMS | Grade | |
Lead Time | 3Day (s) | Origin | Loading Port |
Boiling Point | 449.6ºC at 760mmHg |
---|---|
Appearance & Physical State | crystalline solid |
Flash Point | 225.7ºC |
Refractive Index | 1.593 |
Density | 1.154g/cm3 |
Melting Point | 231-232ºC |
Uses Synthetic retinoic acid receptor-a/?selective retinoid. Antineoplastic
Uses Synthetic retinoic acid receptor-α/β-selective retinoid. Antineoplastic.
Uses A RARα agonist that induces differentiation and apoptosis
Uses Tamibarotene, a retinoic acid receptor-α(RARα) agonist, was approved for the treatment of relapsed or refractory acute promyelocytic leukemia (APL) in Japan on June, 2005 and is currently marketed by Nippon Shinyaku Co. This novel drug has shown high remission rate among patients who have recurrent disease after all trans retinoic acid therapy.
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