10alpha-methoxy-9,10-dihydrolysergol
CAS NO.: 35121-60-9
Purity :99.3%
Compound | Polymyxin B sulfate | ||||
---|---|---|---|---|---|
CAS No. | 1405-20-5 | Catalog No. | po-140 | Brand | |
Purity | 99% | Packing | 1kg | Grade | |
Lead Time | 14Day (s) | Origin | Loading Port |
Boiling Point | 1651ºC at 760 mmHg |
---|---|
Storage Condition | 2-8ºC |
Appearance & Physical State | White crystalline powder |
Flash Point | 952.3ºC |
Vapor Pressure | 0mmHg at 25°C |
Syntheticdescription of the product:PolymyxinB is an antibiotic primarily used for resistant Gram-negativeinfections. It is derived from the bacterium Bacillus polymyxa.Polymyxin B is a mixture of two closely related compounds, polymyxin B1 andpolymyxin B2. It has a bactericidal action against almost all Gram-negativebacilli except the Proteus group. Polymyxins bind to the cellmembrane and alter its structure, making it more permeable. The resulting wateruptake leads to cell death. Polymyxins are cationic,basic proteins that act like detergents (surfactants).Side effects include neurotoxicity and acute renal tubular necrosis. Polymyxinsare used in the topical first-aid preparation Neosporin.Familyof polypeptides with attached fatty acid; cationicdetergentat physiological pH, both hydrophilic and hydrophobic propertiesBactericidalfor gram-negative;little to no effect on gram-positive, since cell wall is too thick topermit access to membrane.
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