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SECTION 1: Identification of the substance/mixture and of the company/undertaking
  Product identifiers
    Product name        : D4 Cyclomethicone    
    REACH No.        : A registration number is not available for this substance as the substance    
    or its uses are exempted from registration, the annual tonnage does not
    require a registration or the registration is envisaged for a later
    registration deadline.
    CAS-No.        : 556-67-2    
  Relevant identified uses of the substance or mixture and uses advised against
    Identified uses        : Laboratory chemicals, Manufacture of substances    
  
  

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SECTION 2: Hazards identification
  Classification of the substance or mixture
  Classification according to Regulation (EC) No 1272/2008
    Flammable liquids (Category 3), H226
    Reproductive toxicity (Category 2), H361
    Chronic aquatic toxicity (Category 4), H413
    For the full text of the H-Statements mentioned in this Section, see Section 16.
  Classification according to EU Directives 67/548/EEC or 1999/45/EC
    R10
    Xn Harmful        R62    
    R53
    For the full text of the R-phrases mentioned in this Section, see Section 16.
  Label elements
  Labelling according Regulation (EC) No 1272/2008
    Pictogram
    Signal word        Warning    
    Hazard statement(s)
    H226        Flammable liquid and vapour.    
    H361        Suspected of damaging fertility or the unborn child.    
    H413        May cause long lasting harmful effects to aquatic life.    
    Precautionary statement(s)
    P281        Use personal protective equipment as required.    
    Supplemental Hazard        none    
    Statements
  Other hazards
    This substance/mixture contains no components considered to be either persistent, bioaccumulative and
    toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

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SECTION 3: Composition/information on ingredients
  Substances
    Molecular weight        : 296,62 g/mol    
    CAS-No.        : 556-67-2    
    EC-No.        : 209-136-7    
    Index-No.        : 014-018-00-1    
  Hazardous ingredients according to Regulation (EC) No 1272/2008
    Component        Classification        Concentration    
  Octamethylcyclotetrasiloxane
    CAS-No.        556-67-2        Flam. Liq. 3; Repr. 2; Aquatic        <= 100 %    
    EC-No.        209-136-7        Chronic 4; H226, H361, H413    
    Index-No.        014-018-00-1    
  Hazardous ingredients according to Directive 1999/45/EC
    Component        Classification        Concentration    
  Octamethylcyclotetrasiloxane
    CAS-No.        556-67-2        Xn, Repr.Cat.3, R10 - R53 -        <= 100 %    
    EC-No.        209-136-7        R62    
    Index-No.        014-018-00-1    
    For the full text of the H-Statements and R-Phrases mentioned in this Section, see Section 16

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SECTION 4: First aid measures
  Description of first aid measures
  General advice
    Consult a physician. Show this safety data sheet to the doctor in attendance.
  If inhaled
    If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
  In case of skin contact
    Wash off with soap and plenty of water. Consult a physician.
  In case of eye contact
    Flush eyes with water as a precaution.
  If swallowed
    Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with
    water. Consult a physician.
  Most important symptoms and effects, both acute and delayed
    The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in
    section 11
  Indication of any immediate medical attention and special treatment needed
    No data available

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SECTION 5: Firefighting measures
  Extinguishing media
  Suitable extinguishing media
    Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
  Special hazards arising from the substance or mixture
    Carbon oxides, silicon oxides
  Advice for firefighters
    Wear self-contained breathing apparatus for firefighting if necessary.
  Further information
    Use water spray to cool unopened containers.

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SECTION 6: Accidental release measures
  Personal precautions, protective equipment and emergency procedures
    Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure
    adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Avoid breathing
    dust.
    For personal protection see section 8.
  Environmental precautions
    Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the
    environment must be avoided.
  Methods and materials for containment and cleaning up
    Sweep up and shovel. Contain spillage, and then collect with an electrically protected vacuum cleaner or
    by wet-brushing and place in container for disposal according to local regulations (see section 13). Keep
    in suitable, closed containers for disposal. Contain spillage, pick up with an electrically protected vacuum
    cleaner or by wet-brushing and transfer to a container for disposal according to local regulations (see
    section 13).
  Reference to other sections
    For disposal see section 13.

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SECTION 7: Handling and storage
  Precautions for safe handling
    Avoid contact with skin and eyes. Avoid formation of dust and aerosols.
    Provide appropriate exhaust ventilation at places where dust is formed.Keep away from sources of ignition
    - No smoking.Take measures to prevent the build up of electrostatic charge.
    For precautions see section 2.2.
  Conditions for safe storage, including any incompatibilities
    Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
    Store at Room Temperature.
    Storage class (TRGS 510): Flammable liquids
  Specific end use(s)
    Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

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SECTION 8: Exposure controls/personal protection
  Control parameters
  Components with workplace control parameters
  Exposure controls
  Appropriate engineering controls
    Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and
    at the end of workday.
  Personal protective equipment
  Eye/face protection
    Safety glasses with side-shields conforming to EN166 Use equipment for eye protection tested
    and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
  Skin protection
    Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
    (without touching glove's outer surface) to avoid skin contact with this product. Dispose of
    contaminated gloves after use in accordance with applicable laws and good laboratory practices.
    Wash and dry hands.
    The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and
    the standard EN 374 derived from it.
  Body Protection
    impervious clothing, Flame retardant antistatic protective clothing., The type of protective
    equipment must be selected according to the concentration and amount of the dangerous
    substance at the specific workplace.
  Respiratory protection
    Where risk assessment shows air-purifying respirators are appropriate use a full-face particle
    respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering
    controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use
    respirators and components tested and approved under appropriate government standards such
    as NIOSH (US) or CEN (EU).
  Control of environmental exposure
    Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into
    the environment must be avoided.

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SECTION 9: Physical and chemical properties
  Information on basic physical and chemical properties
    a) Appearance        Form: clear, liquid    
    Colour: colourless
    b) Odour        No data available    
    c) Odour Threshold        No data available    
    d) pH        No data available    
    e) Melting point/freezing        Melting point/freezing point: 17,7 °C at 1.013 hPa    
    point
    f) Initial boiling point and 175 °C at 1.013 hPa
    boiling range
    g) Flash point        55 °C - closed cup    
    h) Evaporation rate        No data available    
    i) Flammability (solid, gas) No data available
    j) Upper/lower        Upper explosion limit: 7,4 %(V)    
    flammability or        Lower explosion limit: 0,75 %(V)    
    explosive limits
    k) Vapour pressure        1,32 hPa at 25 °C    
    l) Vapour density        10,24 - (Air = 1.0)    
    m) Relative density        0,95 g/cm3 at 25 °C    
    n) Water solubility        0,07 g/l at 25 °C - insoluble    
    o) Partition coefficient: n- No data available
    octanol/water
    p) Auto-ignition        384 - 387 °C at 1.013,0 hPa    
    temperature
    q) Decomposition        No data available    
    temperature
    r) Viscosity        No data available    
    s) Explosive properties        No data available    
    t) Oxidizing properties        No data available    
  Other safety information
    Relative vapour density 10,24 - (Air = 1.0)

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SECTION 10: Stability and reactivity
  Reactivity
    No data available
  Chemical stability
    Stable under recommended storage conditions.
  Possibility of hazardous reactions
    No data available
  Conditions to avoid
    Heat, flames and sparks.
  Incompatible materials
    Strong oxidizing agents, acids, Bases
  Hazardous decomposition products
    Other decomposition products - No data available
    In the event of fire: see section 5

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SECTION 11: Toxicological information
  Information on toxicological effects
  Acute toxicity
    LD50 Oral - Rat - > 2.000 mg/kg
    LC50 Inhalation - Rat - 4 h - 36.000 mg/m3
    Remarks: Behavioral:Excitement. Lungs, Thorax, or Respiration:Dyspnea. Skin and Appendages: Other:
    Hair.
    LD50 Dermal - Rabbit - > 4.640 mg/kg
  Skin corrosion/irritation
    Skin - Rabbit
    Result: No skin irritation - 24 h
    (OECD Test Guideline 404)
  Serious eye damage/eye irritation
    Eyes - Rabbit
    Result: No eye irritation - 24 h
    (OECD Test Guideline 405)
  Respiratory or skin sensitisation
    Maximisation Test (GPMT) - Guinea pig
    Result: Does not cause skin sensitisation.
    (OECD Test Guideline 406)
  Germ cell mutagenicity
    S. typhimurium
    Result: negative
    Mutagenicity (micronucleus test)
    Rat - male and female
    Result: negative
  Carcinogenicity
    IARC:        No component of this product present at levels greater than or equal to 0.1% is identified as    
    probable, possible or confirmed human carcinogen by IARC.
  Reproductive toxicity
    Suspected human reproductive toxicant
    Reproductive toxicity - Rat - Inhalation
    Effects on Newborn: Live birth index (# fetuses per litter; measured after birth).
    Overexposure may cause reproductive disorder(s) based on tests with laboratory animals.
  Specific target organ toxicity - single exposure
    No data available
  Specific target organ toxicity - repeated exposure
    No data available
  Aspiration hazard
    No data available
  Additional Information
    Repeated dose toxicity - Rabbit - male and female - Dermal
    RTECS: Not available
    To the best of our knowledge, the chemical, physical, and toxicological properties have not been
    thoroughly investigated.

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SECTION 12: Ecological information
  Toxicity
    Toxicity to fish        LC50 - Leuciscus idus (Golden orfe) - 200,0 mg/l - 96 h    
    Toxicity to daphnia and EC50 - Daphnia magna (Water flea) - > 0,015 mg/l - 48 h
    other aquatic
    invertebrates
    Toxicity to algae        EC50 - Selenastrum capricornutum (green algae) - > 0,022 mg/l - 96 h    
  Persistence and degradability
    No data available
  Bioaccumulative potential
    Bioaccumulation        Pimephales promelas (fathead minnow) - 0,160 µg/l    
    Bioconcentration factor (BCF): 12.400
    Pimephales promelas (fathead minnow) - 28 d
    - 0,160 µg/l
    Bioconcentration factor (BCF): 14.261
  Mobility in soil
    No data available
  Results of PBT and vPvB assessment
    This substance/mixture contains no components considered to be either persistent, bioaccumulative and
    toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
  Other adverse effects

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SECTION 13: Disposal considerations
  Waste treatment methods
  Product
    Burn in a chemical incinerator equipped with an afterburner and scrubber but exert extra care in igniting
    as this material is highly flammable. Offer surplus and non-recyclable solutions to a licensed disposal
    company. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator
    equipped with an afterburner and scrubber.
  Contaminated packaging
    Dispose of as unused product.

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SECTION 14: Transport information
  UN number
    ADR/RID: 1993        IMDG: 1993        IATA: 1993    
  UN proper shipping name
    ADR/RID: FLAMMABLE LIQUID, N.O.S. (Octamethylcyclotetrasiloxane)
    IMDG: FLAMMABLE LIQUID, N.O.S. (Octamethylcyclotetrasiloxane)
    IATA:        Flammable liquid, n.o.s. (Octamethylcyclotetrasiloxane)    
  Transport hazard class(es)
    ADR/RID: 3        IMDG: 3        IATA: 3    
  Packaging group
    ADR/RID: III        IMDG: III        IATA: III    
  Environmental hazards
    ADR/RID: no        IMDG Marine pollutant: no        IATA: no    
  Special precautions for user
    No data available

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SECTION 15: Regulatory information
    This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
  Safety, health and environmental regulations/legislation specific for the substance or mixture
    No data available
  Chemical Safety Assessment
    For this product a chemical safety assessment was not carried out

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SECTION 16: Other information
  Full text of H-Statements referred to under sections 2 and 3.
    Aquatic Chronic        Chronic aquatic toxicity    
    Flam. Liq.        Flammable liquids    
    H226        Flammable liquid and vapour.    
    H361        Suspected of damaging fertility or the unborn child.    
    H413        May cause long lasting harmful effects to aquatic life.    
    Repr.        Reproductive toxicity    
  Full text of R-phrases referred to under sections 2 and 3
    Xn        Harmful    
    R10        Flammable.    
    R53        May cause long-term adverse effects in the aquatic environment.    
    R62        Possible risk of impaired fertility.    
    Repr.Cat.3        Toxic to Reproduction Category 3    
  Further information
    Copyright 2014 Co. LLC. License granted to make unlimited paper copies for internal use
    only.
    The above information is believed to be correct but does not purport to be all inclusive and shall be
    used only as a guide. The information in this document is based on the present state of our knowledge
    and is applicable to the product with regard to appropriate safety precautions. It does not represent any
    guarantee of the properties of the product. Corporation and its Affiliates shall not be held
    liable for any damage resulting from handling or from contact with the above product. See
     and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.