Hyaluronic acid (HA; conjugate base hyaluronate), also called hyaluronan, is an anionic, nonsulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues. It can be extracted from rooster combs or produced by bacterial fermentation. Its unique molecular structure and physicochemical properties have many important physiological functions inside the body, such as lubricating joints, adjusting vascular permeability, adjusting proteins, diffusing and transporting water electrolytes, and promoting wound healing. Hyaluronic acid has a unique water retention effect and has the best known natural moisturizing properties, making it the ideal natural moisturizer.
Pharmaceutical grade Hyaluronic acid can be used as an API or excipient for drugs and medical devices in ophthalmic preparations, in-articular injections, anti-adhesive preparations, topical preparations for wound healing and soft tissue filler, etc. It includes Medical Grade HA and Injection Grade HA.
Item | Intrinsic Viscosity (m3/kg) | Molecular Weight (Da) | Certifications | Functions | Applications | Injection Grade Hyaluronic Acid | FS-HA-EP1.8 | 1.6-2.2 | 800K-1,300K | DMF & CEP & KDMF | Viscoelasticity, protecting corneal endothelium Lubricating, viscoelasticity, repairing damage cartilage, inhibition of inflammation, pain relief, etc. Properties of good biocompatibility and degradability of HA and its derivatives | Ophthalmic viscosurgical devices (OVD) Intra-articular injection Anti-adhesive products, dermal filler, scaffold materials in tissue engineering, etc. | FS-HA-EP3.0 | 2.7-3.6 | 1,600K-2,500K | DMF & CEP & KDMF | FS-HA-EP2 | 0.4-4.0 | 10K-3,000K | DMF (open part) | Medical Grade Hyaluronic Acid | FS-HA-ME2.0 | 1.3-1.5 | 800K-1,300K | DMF | Lubricating, moisturizing, improving efficacy of drugs, relieving dry eye syndrome, and promote healing of corneal and conjunctival injury Wound healing Drug or cell carrier/matrix Repairing damaged mucous membrane or cartilage, etc. | Eye drops, eye lotions, contact lens solutions, medical lubricants, etc. Topical preparations (formulations of gel, film, etc.) Eye drops, cell culture, etc. Oral pharmaceutical preparations | FS-HA-ME3.0 | 2.7-3.6 | 1,600K-2,500K | DMF | FS-HA-ME0.5 | 0.5-1.0 | 20K-60K | DMF | FS-HA-MEP1 | 0.2-4.0 | 10K-3,000K |
| FS-HA-MEP1.0 | <2.5 | <1,500K |
| FS-HA-MEP2.0 | >2.0 | >1,000K |
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Cosmetic Grade Hyaluronic Acid. In cosmetic industry, the formulators are striving to get safer and more efficient cosmetic raw materials. Sodium Hyaluronate (HA), which is well-known as natural moisturizing factor, is just this kind of compound. It enhances the appearance of dry or damaged skin by reducing flaking and restoring suppleness. Hyaluronic Acid is also used to thicken the aqueous (water) portion of cosmetics and personal care products.
Item | Molecular Weight (Da) | Certifications | Functions | Applications | Dosage | Cosmetic Grade Hyaluronic Acid | FS-HA-CH | >1,800K | ECOCERT | Lubricating and film-forming, moisturizing, preventing skin damage, thickening and keeping emulsion stable | Skin care: cream, emulsion, essence, lotion, gel, facial mask, etc. Makeup: lipstick, eye shadow, foundation, etc. Cleansing: facial cleaner, body wash, etc. Hair care: shampoo, hair conditioner, styling gel, hair restorer, etc. | 0.1% ~ 0.5%for HA powder 10% ~ 50% for HA solution 1-5% for Hyacross 0.5-1% for cationHA
| FS-HA-CM | 1,000K-1,800K | ECOCERT | FS-HA-CL | 10K-1,000K | ECOCERT | Nourishing the skin, long-lasting moisturizing | FS-HA-CN | 200K-400K | ECOCERT | FS-HA-Coligo | <10K | ECOCERT | Trans-dermal absorption, deep hydrating, anti-ageing, repairing skin damage | FS-HA-Cmini | <10K | ECOCERT |
Food Grade Hyaluronic Acid. Hyaluronic acid is a linear high molecular weight mucopolysaccharide composed by thousands of repeating disaccharide units of D-glucuronic acid and N-acetyl-D-glucosamine. Oral HA can increase HA content in human body, supply deficiency of HA by digesting and absorbing HA, skin can be made moist, smooth, soft and rich spring. Oral HA can defer crowed senility, prevent arthritis, arteriosclerosis, plus disorder and brain atrophy. Oral HA can make one full of beans and be rich in youth energy
Item | Molecular Weight (Da) | Functions | Applications | Food Grade Hyaluronic Acid | FS-HA-F | 200K-600K | Helps promote joint health Helps restore skin moisture and improve skin health | Common food: beverage, jelly, dairy products, etc. Health food: usually in combination with Collagen, Vitamins, Chondroitin Sulphate, or Glucosamine to make tablets, capsules or oral liquid these popular forms | FS-HA-FC | Customized molecular weight | FS-HA-FH | >1,800K | FS-HA-FM | 800K-1,600K | FS-HA-FL | 10K-1,000K | FS-HA-FN | 200K-600K |
Freshine Chemicals can supply each specification hyaluronic acid of pharmaceutical grade, cosmetic grade and food grade.
FreShine Chemicals Company were established on July, 2014. We are focusing on the future technology of cosmetic industry, including formulating R&D research, patent transfer service and special materials supply. We offer innovation support to cosmetic R&D and manufacturing for personal care, household care and health & beauty. To meet the increasing demands of chemicals in cosmetic industry, FreShine Chemicals Company carries hundreds of special raw materials. We sincerely look forward to cooperate with formulators, brand planners and marketing experts to enjoy the technology and create the future. We want to be your integral partner from initial R&D to market promotion. We believe the nature magic and the technology powder. We persist in the idea that technology creates healthy beauty. What We Do: Relying on the largest-scale manufacturer in the world, we offer global customers Ascorbyl Glucoside, a highly effective skin whitening agent with high quality and competitive price. We supply the personal & household care industry with the multi-functional solutions leading the trend of natural plant technology. We distribute special home & personal care raw materials from high-quality manufacturers and offer formulation application service.
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